Population genetics and GWAS: A primer.
نویسنده
چکیده
This primer provides some background to help non-specialists understand a new theoretical evolutionary genetics study that helps explain why thousands of variants of small effect contribute to complex traits.
منابع مشابه
Genome-wide association studies: a primer.
There have been nearly 400 genome-wide association studies (GWAS) published since 2005. The GWAS approach has been exceptionally successful in identifying common genetic variants that predispose to a variety of complex human diseases and biochemical and anthropometric traits. Although this approach is relatively new, there are many excellent reviews of different aspects of the GWAS method. Here...
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ورودعنوان ژورنال:
- PLoS biology
دوره 16 3 شماره
صفحات -
تاریخ انتشار 2018